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The thiopurine S-methyltransferase gene locus -- implications for clinical pharmacogenomics. Azathioprine and mercaptopurine are moderately bound to serum proteins 30 and are partially dialyzable. The relative incidences in clinical studies are summarized below: Toxicity Renal Homograft Rheumatoid Arthritis Leukopenia any degree 50 28 um generic imuran 2500 cells mm3 16.
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We comply with the HONcode standard for trustworthy health information. MedicineNet does not provide medical advice, diagnosis or treatment. Patients online imuran kjop with two non-functional alleles homozygous have low or absent TPMT activity and those with one non-functional allele heterozygous have intermediate activity. Check the label on the medicine for exact dosing instructions.
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